Carr lab

Antibody Selection Laboratory

We want to understand why antibody responses are different between individuals after an identical immune challenge, such as vaccination with a previously unencountered antigen. 

We research exactly what these differences are, how each individual’s immune system creates them and how we might be able to use or modify these differences to make someone’s immune response stronger or more focused for therapeutic purposes. Our main focus is on respiratory infections, but this could also be applied to other infectious diseases, or any antibody response including autoimmunity.

A large part of the lab’s work is collaborative, both within the Crick, working closely with the Legacy study, the Covid Surveillance Unit and the Worldwide Influenza Centre; across the UK working with the UK Health Security Agency’s SIREN study; and internationally working with WWW consortium.
 
Potential collaborators, PhD students, post-doctoral researchers and clinicians are encouraged to contact the lab.