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Intro

Our mission is to pursue scientific research without boundaries. We aim for our research to be open, accessible and reproducible.

We publish the new ideas, knowledge and techniques that emerge from Crick research as peer-reviewed papers.

All of our primary research is open access, meaning it can be accessed free online.

We believe that freely accessible research is good for science. It removes barriers to accessing and analysing research and data, so research can be built upon and reaches the widest possible audience.

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Publication highlights

We've collected some of the most significant papers published by Crick researchers so far.

View the highlights

Latest Publications

Displaying 1 - 11 of 11
Last updated : 03 March 2026 03:12

Immunogenomics of colorectal cancer response to checkpoint blockade: analysis of the KEYNOTE 177 trial and validation cohorts

Authors (29)

The transcription co-repressors MTG8 and MTG16 regulate exit of intestinal stem cells from their niche and differentiation into enterocyte vs secretory lineages

Authors (11)
  • Anna Baulies Domenech
  • Nikolaos Angelis
  • Valentina Foglizzo
  • Erik Danielsen
  • Harshil Patel
  • Laura Novellasdemunt
  • Ania Kucharska
  • Joana Do Vale Viegas Silva Carvalho
  • Emma Nye
  • Paolo De Coppi
  • Vivian Li

Identification of subtypes of Barrett's esophagus and esophageal adenocarcinoma based on DNA methylation profiles and integration of transcriptome and genome data

Authors (19)
  • SriGanesh Jammula
  • Annalise C Katz-Summercorn
  • Xiaodun Li
  • Constanza Linossi
  • Elizabeth Smyth
  • Sarah Killcoyne
  • [...]
  • Nicola Grehan
  • Matthew D Eldridge
  • Simon Tavaré
  • Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) consortium
  • Rebecca C Fitzgerald
Published