Mouse colony management: GA strain creation, validation, welfare and breeding

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Fee: £ 825

This course, held at the Francis Crick Institute in London, is aimed at colony managers, experienced/senior animal technicians, facility managers, and researchers (including PhD students). 

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Course info

This course, held at the Francis Crick Institute in London, is aimed at colony managers, experienced/senior animal technicians, facility managers, and researchers (including PhD students). 

Taking place across three days, a range of Crick experts will share a blend of current best practice theory and real-world challenges. Participants will have the opportunity to get hands on by planning and optimising breeding crosses, and analysing genetic background report data, as well as peeking behind the barrier with a facility tour.  

The course also offers valuable time for participants to discuss and share their own workplace challenges, and to learn from each another through conversation and active participation. 

Topics covered include: 

  • Mouse model types, application and availability  
  • Strain importation and rederivation  
  • Genetically altered strain creation  
  • Genetically altered breeding, good practice and breeding calculations
  • Strain welfare monitoring and phenotyping  
  • Caring for immunocompromised mice  
  • Health monitoring  
  • Genetic monitoring
  • Cryopreservation and assisted reproductive technologies   
  • Mouse microbiome 
     

The course has been developed by the Colony Management Services team, which sits within the Crick’s Biological Research Facility, providing a flexible and comprehensive package of support that enables the efficient and effective management of mouse colonies at the institute. Ensuring reliable and reproducible research, and best practice in animal welfare, is at the heart of everything the team does. 

By the end of this training, participants will be able to: 

  • Explain the key factors required for optimal colony management
  • Select and apply useful tips and tools to assist with implementation of optimal colony management
  • Describe and apply the organisational management structures and services necessary for optimal CM
  • Summarise quality assurance and maintenance processes of inbred and GA strains, and evaluate their own set up to implement relevant pipelines
  • Evaluate data analysis for GA colonies, with particular reference to genetic background and microbiome 

Places on this training event are strictly limited. Candidates are required to apply by completing the form below, by Sunday 7 June 2025, detailing their relevant experience and the expected impact of this training on their professional practice. Applications will be reviewed by the lead educators and successful candidates will be invited to register.   

Registration fees are £825, though discounted registration fees of £660 are available to staff and students from Imperial College London, UCL (University College London) and King’s College London. 

Applications will be reviewed on a rolling basis and will close once all spots are filled, so apply at your earliest convenience to avoid disappointment. 

This training is approved by the Royal Society of Biology. Training course approval is an independent review process that recognises relevant, high-quality training. Upon completion of this course, participants can claim 54 CPD points. 

By applying and/or registering to this course, you acknowledge that you have read, understood, and agreed to the Terms and Conditions.

Have a question?

Contact our technical training team at techtraining@crick.ac.uk

Application form

Approximately 200 words.
Approximately 200 words.
What is your current level of understanding of genetics and breeding (e.g., Mendelian inheritance and genotyping)?
Approximately 200 words.

RSB approved

Royal Society of Biology logo

This training event is sponsored by Transnetyx

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