Lucy Collinson
Head of Electron Microscopy
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Dr Lucy Collinson is an electron microscopist with a background in microbiology and cell biology.
She has a degree and PhD in Medical Microbiology, and carried out post-doctoral research with Professor Colin Hopkins at the MRC Laboratory for Molecular Cell Biology (UCL) and Imperial College London, investigating membrane trafficking pathways in lysosome-related organelles in mammalian cells using light and electron microscopy as key techniques.
She has run a series of biological electron microscopy facilities since 2004, at UCL and then at the Cancer Research UK London Research Institute, which became part of the new Francis Crick Institute in 2015. With a team of 10 electron microscopists and 3 physicists, she oversees more than 100 research projects with more than 60 research groups within the Crick, imaging across scales from proteins to whole organisms.
Her microscopy and technology development interests include volume EM, correlative imaging techniques, cryo-microscopy, X-ray microscopy, image analysis, and microscope design and prototyping.
Her group is using Citizen Science to gather hundreds of thousands of annotations of EM images to train deep machine learning algorithms to automatically recognise organelles in EM images through the Etch a Cell project on the Zooniverse platform.
She is committed to open science through sharing of image data, protocols, software and hardware designs.
She has co-authored more than 80 research and review papers, given more than 70 invited and keynote talks, and has sat on more than 30 international advisory boards, panels and committees in advanced imaging.
Qualifications and history
Year published
Research topics
- Biochemistry & Proteomics (28)
- Cell Biology (42)
- Cell Cycle & Chromosomes (10)
- Chemical Biology & High Throughput (18)
- Computational & Systems Biology (22)
- Developmental Biology (12)
- Ecology,Evolution & Ethology (3)
- Gene Expression (3)
- Genetics & Genomics (11)
- Genome Integrity & Repair (9)
- Human Biology & Physiology (12)
- Imaging (92)
- Immunology (19)
- Infectious Disease (24)
- Metabolism (6)
- Microfabrication & Bioengineering (4)
- Model Organisms (38)
- Neurosciences (9)
- Signalling & Oncogenes (17)
- Stem Cells (8)
- Structural Biology & Biophysics (10)
- Tumour Biology (17)
Crick Pre-Crick
Publication type
Journal
- Applied Physics Letters (2)
- Biochemical Society Transactions (1)
- Bioinformatics (1)
- Biomaterials (1)
- BioRxiv (8)
- BMC Biology (1)
- British Journal of Ophthalmology (1)
- Cancer Discovery (2)
- Cell (2)
- Cell Host and Microbe (3)
- Cell Reports (2)
- Cell Reports Methods (1)
- Current Opinion in Biomedical Engineering (1)
- Development (1)
- Disease Models and Mechanisms (1)
- eLife (7)
- EMBO Molecular Medicine (1)
- EMBO Reports (2)
- Faraday Discussions (1)
- Frontiers in Cell and Developmental Biology (1)
- Gene Therapy (1)
- Histochemistry and Cell Biology (1)
- Immunity (1)
- JCI insight (1)
- Journal of Cell Biology (1)
- Journal of Cell Science (6)
- Journal of Chemical Biology (2)
- Journal of Clinical Investigation (2)
- Journal of Experimental Medicine (1)
- Journal of Imaging (1)
- Journal of Lipid Research (2)
- Journal of Microscopy (2)
- Journal of Physics D: Applied Physics (1)
- Journal of Structural Biology (1)
- Life Science Alliance (1)
- mBio (3)
- medRxiv (1)
- Methods in Cell Biology (5)
- Micron (1)
- Molecular Biology of the Cell (2)
- Molecular Cell (1)
- Molecular Endocrinology (1)
- mSphere (1)
- Nature (3)
- Nature Cell Biology (5)
- Nature Communications (8)
- Nature Immunology (1)
- Nature Medicine (1)
- Nature Methods (7)
- Nature Neuroscience (1)
- Nature Protocols (1)
- Nature Reviews Methods Primers (1)
- Nature Structural and Molecular Biology (1)
- Neuromethods (1)
- Particle and Fibre Toxicology (1)
- PLOS Biology (2)
- PLOS ONE (2)
- PLOS Pathogens (1)
- Proceedings of the National Academy of Sciences of the United States of America (2)
- Protoplasma (1)
- Science (4)
- Science advances (1)
- Science Translational Medicine (1)
- SLAS Discovery (1)
- STAR Protocols (1)
- Tissue Engineering Part A (1)
- Traffic (1)
- Ultramicroscopy (2)
- Wellcome Open Research (1)