James Briscoe
Principal Group Leader - Associate Research Director
James Briscoe is a senior group leader. He obtained a BSc in Microbiology and Virology from the University of Warwick, UK. Following his PhD research in Ian Kerr's laboratory at the Imperial Cancer Research Fund, London (which became Cancer Research UK and is now part of the Francis Crick Institute), he undertook postdoctoral training at Columbia University, New York, USA, with Thomas Jessell, first as a Human Frontiers Science Program Fellow then as a Howard Hughes Medical Institute Fellow.
In 2000 he moved to the Medical Research Council's National Institute for Medical Research (now part of the Francis Crick Institute) to establish his own research group and in 2001 he was elected an EMBO Young Investigator. He was awarded the EMBO Gold Medal in 2008 and elected to EMBO in 2009. In 2018 he became Editor in Chief of Development, a journal published by the Company of Biologists, a not-for-profit scientific publisher. He was elected a Fellow of the Academy of Medical Sciences and a Fellow of the Royal Society in 2019.
His research interests include the molecular and cellular mechanisms of graded signalling by morphogens and the role of transcriptional networks in the specification of cell fate. To address these questions his lab uses a range of experimental and computational techniques with model systems that include mouse and chick embryos and embryonic stem cells.
Qualifications and history
Year published
Research topics
- Biochemistry & Proteomics (7)
- Cell Biology (12)
- Cell Cycle & Chromosomes (2)
- Chemical Biology & High Throughput (7)
- Computational & Systems Biology (98)
- Developmental Biology (99)
- Ecology,Evolution & Ethology (1)
- Gene Expression (97)
- Genetics & Genomics (12)
- Genome Integrity & Repair (7)
- Human Biology & Physiology (10)
- Imaging (9)
- Immunology (7)
- Infectious Disease (9)
- Metabolism (1)
- Microfabrication & Bioengineering (1)
- Model Organisms (95)
- Neurosciences (94)
- Signalling & Oncogenes (95)
- Stem Cells (8)
- Synthetic Biology (94)
- Tumour Biology (10)
Crick Pre-Crick
Publication type
Journal
- Annual Review of Cell and Developmental Biology (1)
- Biol Open (1)
- BioRxiv (13)
- BMC Biology (1)
- Cancer Research (1)
- Cell (3)
- Cell Death and Differentiation (1)
- Cell systems (6)
- Current Biology (1)
- Current Opinion in Genetics and Development (3)
- Current Topics in Developmental Biology (3)
- Development (44)
- Developmental Cell (13)
- Disease Models & Mechanisms (1)
- Disease Models and Mechanisms (1)
- eLife (2)
- EMBO Journal (1)
- EMBO Reports (1)
- Genes & Development (1)
- Human Molecular Genetics (1)
- Interface focus (2)
- International Journal of Developmental Biology (1)
- Journal of Cell Science (1)
- Journal of Computational Biology (1)
- Journal of Experimental Biology (1)
- Journal of the Royal Society Interface (2)
- Mechanisms of Development (1)
- Methods in Molecular Biology (1)
- Nature (2)
- Nature Biotechnology (1)
- Nature Cell Biology (2)
- Nature Communications (4)
- Nature Immunology (2)
- Nature Neuroscience (1)
- Nature Reviews Molecular Cell Biology (2)
- Nucleic Acids Research (1)
- Physical Review Research (1)
- PLOS Biology (10)
- PLoS Computational Biology (2)
- PLOS Genetics (2)
- PLOS ONE (1)
- Proceedings of the National Academy of Sciences of the United States of America (2)
- Science (6)
- Science Signaling (1)
- Scientific Reports (1)
- STAR Protocols (1)
- Stem Cells (1)
- The EMBO Journal (2)
- Trends in Cell Biology (1)
- Trends in Genetics (1)
- Wellcome Open Research (2)
- Wiley Interdisciplinary Reviews. Developmental Biology (2)