We are a multidisciplinary group of immunologists, cell biologists and clinical academics who aim to understand the molecular mechanisms underlying common lung diseases, including asthma and fibrotic lung diseases.
Our lab explores the interactions between lung cells and infiltrating inflammatory cells to determine how these interactions influence the development and resolution of pulmonary inflammation during a range of different lung diseases. We use a mixture of mouse models and culture systems using cells from patients to investigate the mechanisms underlying the pulmonary immune response to inhaled particles, allergens and pathogens.
Broadly our research encompasses three areas: immune regulation in the lung, pulmonary immunity in early life and the development of lung remodelling.