Birgit Aerne

Principal Laboratory Research Scientist

Image of the histoblasts, the cells that form the abdomen of the adult fruit fly.

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Apoptosis and Proliferation Control Laboratory

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Last updated : 03 March 2026 03:53

Meru co-ordinates spindle orientation with cell polarity and cell cycle progression

Authors (6)

Melissa Mclellan
Birgit Aerne
Jennifer J Banerjee Dhoul
Maxine Holder
Tania Auchynnikava
Nicolas Tapon

EMBO Journal

Published 16 May 2025

Crick labs/ facilities

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TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling

Authors (39)

Wei-Ting Lu
Lykourgos-Panagiotis Zalmas
Chris Bailey
James RM Black
Carlos Martinez-Ruiz
Oriol Pich
[...]
Kasper Fugger
Nicholas McGranahan
Jiri Bartek
Nnennaya Kanu
Charles Swanton

Nature Cell Biology

Published 1 January 2025

Crick labs/ facilities

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Growth compensation upon changes in tissue size in the Drosophila abdomen

Preprint

Authors (8)

Ana De Almeida Ferreira
Andrea Cairoli
Federica Mangione
Maxine Holder
Anna Ainslie
Birgit Aerne
Guillaume Salbreux
Nicolas Tapon

bioRxiv

Published 3 October 2024

Crick labs/ facilities

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The Drosophila ecdysone receptor promotes or suppresses proliferation according to ligand level

Authors (6)

Gantas Perez Mockus
Luca Cocconi
Cyrille Alexandre
Birgit Aerne
Guillaume Salbreux
Jean-Paul Vincent

Developmental Cell

Published 23 October 2023

Crick labs/ facilities

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RASSF8-mediated transport of Echinoid via the exocyst promotes Drosophila wing elongation and epithelial ordering

Authors (8)

Eunice HY Chan
Yanxiang Zhou
Birgit Aerne
Maxine Holder
Anne Weston
David Barry
Lucy Collinson
Nicolas Tapon

Development

Published 15 October 2021

Crick labs/ facilities

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Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division

Authors (6)

Jennifer J Banerjee
Birgit Aerne
Maxine Holder
Simon Hauri
Matthias Gstaiger
Nicolas Tapon

eLife

Published 30 June 2017

Crick labs/ facilities

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The Hippo pathway core cassette regulates asymmetric cell division

Authors (6)

Alyona Keder
Noemí Rives-Quinto
Birgit Aerne
Maribel Franco
Nicolas Tapon
Ana Carmena

Current Biology

Published 2 November 2015

Crick labs

Nic Tapon

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Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous system

Authors (3)

Proceedings of the National Academy of Sciences of the United States of America

Published 15 September 2015

Crick labs/ facilities

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Hippo stabilises its adaptor Salvador by antagonising the HECT ubiquitin ligase Herc4

Authors (4)

Birgit Aerne
Ieva Gailite
David Sims
Nicolas Tapon

PLOS ONE

Published 30 June 2015

Crick labs

Nic Tapon

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Zyxin antagonizes the FERM protein expanded to couple F-actin and Yorkie-dependent organ growth

Authors (5)

Pedro Gaspar
Maxine Holder
Birgit Aerne
Florence Janody
Nicolas Tapon

Current Biology

Published 16 March 2015

Crick labs

Nic Tapon

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Birgit Aerne

Principal Laboratory Research Scientist

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Meru co-ordinates spindle orientation with cell polarity and cell cycle progression

TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling

Growth compensation upon changes in tissue size in the Drosophila abdomen

The Drosophila ecdysone receptor promotes or suppresses proliferation according to ligand level

RASSF8-mediated transport of Echinoid via the exocyst promotes Drosophila wing elongation and epithelial ordering

Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division

The Hippo pathway core cassette regulates asymmetric cell division

Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous system

Hippo stabilises its adaptor Salvador by antagonising the HECT ubiquitin ligase Herc4

Zyxin antagonizes the FERM protein expanded to couple F-actin and Yorkie-dependent organ growth

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